The discussion about energy refurbishments is defined by high complexity. If house owners or policy makers have to identify appropriate energy standards for their buildings or the existing stock, various aspects of different disciplines (e.g. economics, ecology, building physics, architecture, ...) have their place and must taken into account. The amount of disciplinary studies on the effects of energetic retrofits grows steadily, and every discipline proofs their numbers continuously. Nevertheless, in disciplinary research, interdependencies between the various relevant aspects of the involved disciplines remain open. _This paper aims to reduce the complexity by creating transparency as well as to identify particularly efficient measures for the residential refurbishments. _In a case study on exemplary residential buildings, different measures of energetic retrofitting are analyzed in terms of their impact on various aspects, which are relevant to diverse disciplines (i.e. temperature effects, GWP, incremental costs for energy savings, ...). The identified effects show in detail the efficiency of different measures as well as their reciprocal interactions. Hence, the results provide both a guideline of beneficial measures of energetic refurbishments and a useful sequence order for house owners. Further, a transparent basis for policy implications about future levels of legal requirements for energy usage of buildings and funding instruments for energy reduction to each other.